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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89b0e0bbad1721dc0cd3e4c3f8488d1ccdf75d1d48cda038e6f09070eb5f4a72' 
  AND token = 'SamvGmKQ5LO3BISUHHk6F266nOYvmpRUKXNhLIy1Pgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}