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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27520c09204a19d9617c5d4613fddbcc19258ce7bcb30ae98dc02c3d0cf632f3' 
  AND token = 'M/2ndj/2RcFD8u4OloOk6rmzOrb8lpuPSYm3V8oyCig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}