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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5b32860d054be9e26b68477e2190e910799ea257d12b6a8318221a2aab60883' 
  AND token = 'rezimGiCZWly3Po7GO/FFyBsjJY7RJ8P0Pp5cJlmNwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}