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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d3393c2da32478deb143e20dfe315cbad9582274dabe7ed53fe4edd5c3eba1b' 
  AND token = 'rddpcGPmHCxndgcueWTIGb/TRH+Jhd5Zhy/T2t5Bqy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}