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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dacbe79ad0065e0175213e44316603b8916f2d620e2306df41e1dd18a591bf0c' 
  AND token = 'l0xjecMmmcN1qZspZY+prAsYRppDa+sUXXGLPUtvrPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}