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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '786f190014a34ca2303231ac83f5d6eef7fba8a7bf6b170b12f1f6e738d2aee8' 
  AND token = '/R7kNYnNkCbIJtJl1vilK77UfyGDcS9YnhAsZ7WJjjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}