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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1c6f74662b88bf56785213e3fca49953818fdcc337960243bf7498dd2bb7e6a' 
  AND token = 'xXtl7c5zFDgfBT1s/34RkqM2Gsxr7qX0WPr69VhPgnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}