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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c72b45e3efaac8193259fd6102883e6b7517826898157e2783fc61b79df07766' 
  AND token = 'Wwc7pubADZZZeW24x8aiVHg9X/gMFhWDfAsoiLvdVmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}