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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1185b2d9cc3f04bddec301ad72075842a4cd1527d85d66f89e5892a692135050' 
  AND token = 'aRkXQCBXs9RKmIt1l7cbyboA91WQvErCfNUWcnPwTcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}