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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd968ba51561e496ad066cde22f2aaea21f90da844eacad3910cb7b85966b9949' 
  AND token = '0lUu00eIGm//vRNWIlHg5dDpkA+X+oxyxQBQxB+nHf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}