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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fae0d9f059c48d400c63db4e4fd3cfe0742c7862ecaec109d2d671bd516a18a5' 
  AND token = 'BIRJuOY+esRwIm473MNISNbYrZdhK+CANOGGUmyZOhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}