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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c6dca5e46c1e863573bbae4df7ad004077eafaceb48c2362dd3447a57293e87' 
  AND token = 'LMYPXna0z4N1TwF3JZkavFXd0fyIJl/i6hDn/6ROaOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}