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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18460b9f7b24638d74489ae5ad5892100d154670fefe8bae8ff862f26d456dee' 
  AND token = 'ucQPo+35QA1efDrnlpKu+7h7mcmrSDC5jeu3gUxq0iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}