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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b8de5298e88a95ca8d72cebb005bd8b329205310f63e39c4051cb0624e66d5e' 
  AND token = 'qWnRYS6VGaW99cNXs1HQRdAFZmQOdRhDjzMk3QV1XmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}