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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ef2458c585b2511bee6187695700ccab0eaab997ffc03a8bc234f567b6f1036' 
  AND token = 'iOFgIQCQyLTG9kVPCQ+5imGbETT8PNUBzbWrtHJAnm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}