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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a3cb264cb57acf69616e7a41150dffbe99718a07a51a1a9990c8d489124e54b' 
  AND token = 'PQd0/0gLaNFs3jHCI6XcZMzLzfgtx5efphu7nGaFskk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}