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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fea78a0b5d0c7d1238f7f7d70575a9f0a808d50618df3466ed08555b2274b86' 
  AND token = 'kvZ9P6R7s0s+QMq6VZ3S1rWyrtS2x6S0NHFcdy8nALg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}