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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f946c82bcfe4acb1da0327445e214d178af096e8c1e4dc1513bc7ddf2dadd312' 
  AND token = 'S4d4UmL4qfHtkhRdy5j2VIocbd93ldh6+zK2Wg8xEFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}