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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '849b88f5fa575498c3ece8f637f52877a0f385ce092ceebaec35d6a880456d06' 
  AND token = 'lbj+09niwgHpBqGbFY768IyqbqfgHUl9U0B8rR1IV0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}