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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2270b668f310783aba2eb503c4b610bee0cf7036a9e35c229cae9389e9402979' 
  AND token = 'GGRC+H/jy8Yk3Hg+cSer5gjCIll0PWAqYew1nV72Wrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}