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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c3b10ee61bb55a433c0f11cf9980674bd38c157db76d1a8b085ad7ad763655c' 
  AND token = 'IJwZpPRgeN+AUrYca+iMjgmAT8/JuXAdcQNd54Mjk7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}