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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ba5eb11bf8ed27260b9b653bb78a6727afd9f9d746420f3e6be62c63ff49e41' 
  AND token = 'XNwmu9qLL3t3tsXNDcDU+BnqekPS+BmzIVY9FyW2EYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}