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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c952cd2a862f130670fb23c9621eeef78790cdd1edee958866485490bb3aea0' 
  AND token = 'OGTzU71f/Vx1HeG1BjZhr5cSZCfwMoEp9Dr0jnC1pio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}