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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2c3c7c991380384b98a7e17bfa7416d3b60d30a0f603faca0d649779b6d4a84' 
  AND token = 'E8sjkMRw61JAySLKm6/uE3viajz1FdepGXUiZj9Pa/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}