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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f45cd5957049feffd13df7a5757e5a8607eafaf3675b3a5336c911664b0b27d4' 
  AND token = 'HnJ8wV4Y56jdSc3m/OnCiwHBdaWE3q96CggEM6PKkdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}