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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ed4b8e205e496d12ddb415464fc179f7782fec92c669f00ae02cf15523923f7' 
  AND token = 'b2NOwfBhPmhnUXPss57tdp0DwlWRR17A8KYWLVt8MtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}