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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b6ea1ce59f77a673db4df00430650f512a0a9b0e1347b8aca1472751c2007d6' 
  AND token = 'JUxIN3T/zBLScYoZRPspEY+w5bS8E4pStDyZYNYfrwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}