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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abee7fecfa05e37425109f9677bc5b11253b50f342d02ebb6a3b8d5c7cfb29de' 
  AND token = 'kOwFd8tpHtVPqXeMT3DaPwSnOOckeiY2igP2IiXw9Jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}