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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c72bf434b909eeb5ef08000ece54f3ff6c9bb7f10446c5d7fd2ccdb58348523' 
  AND token = 'UMb7FlJ9fNz/4VQ2Z6VbuqqODb9/Ce/j9Wji9RiwEoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}