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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51e3c64f05aebc8d4db2435fa83f36e6d1bebfd7b48d71d517c187c679be467f' 
  AND token = 'DKCrog1WdF0G5y2u5pVdwDtbaoRfS+ju7HlqL5SbFqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}