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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d80d4778d067fa5747e6ab15714467697e16a0172b5c0ddb1141990cd32e246' 
  AND token = 'XIwoRdl30vzs3aJ3Y6XG/hWVCR6e7TS28hOW+s5KhjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}