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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6345bfa4d716fd3d1a4a270e3ef5f070eeba64fac29007e6e02ed146b915ba6' 
  AND token = 'I+xtMhalgpw6pTUvj/LJf3XkOylGsx/g57N38eI7Z9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}