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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24789d1b760282f43dcf36199a62da6c6b27f3b19c9a922e79d2d661ed47130b' 
  AND token = 'HnlyccsP2//cEvauSog54PC81S600lX3ycKSms4Jk+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}