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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a46635186fda9a6a1a82fc8776031edcf2f6f627ae5ee4eb4090760b76ee4bb0' 
  AND token = 'o8d/y6tuQpdwo0G0c2S/TC8CHoUPpKuCmMXozcgWuh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}