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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '977885db4bd967de25e26dd008ec6d29d801cda4a1c1e223e7bb93ad397f71da' 
  AND token = 'eMtO+Cjs40JBHNtbMdsL+aM4D8ecZ01ReVPZNykJd3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}