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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe2e03b532e951ba1512bda371db8711f07ba4f336f946e66430ab770479bd09' 
  AND token = '4e3CnWixCuGlVW8dWUi2LjN4TG0dPgQFVXrwzfGvaP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}