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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e86d2402459cba94d1b3efa14984ce95c26d5184de39904ad004fc52dc4791' 
  AND token = '+T5HzR5q6Q3H0681DkptDEWb52WVEg/wDu4Zf5RqB0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}