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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea92005c946f99708d964a411409db19d94c2261dbb737429cba5159c39f9d7a' 
  AND token = 'wYegVK960IZVRDGDj4wBgVDDwzPi2c4Kr+w4icMXVCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}