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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50588b7e7793f9cd52074b6ac92736a69170e42b146a974ee7355a87fbf5f209' 
  AND token = 'dqVy4/fneKk4SJjw7cZkDXDP6mwHI/BcPSj8XhD8EK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}