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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b0ae1e8a15e7bf138d202c234153280d023d94d3e9aca3b57ce1d1a766f8ead' 
  AND token = '2UlA4lVV9XmoDYS+fY0DeW3GZJqmjd8DQDdgHF0FbxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}