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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa54763654f12a3954a3533e0f11ea4fdf02a3c9490e94d92cd4f1fbc3fa2005' 
  AND token = 'ZQ5UVj0V/m5/n7Rd+Fx78fLLsdEWaFfa9s67pCnsTcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}