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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6fab6c6de5756236305a23b2485053209592b04f7c3e9451671192417f36218' 
  AND token = 'FseMF/MvF21vMfoBC0PioidymbwDl4QveLd9gSooQrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}