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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd209e41fc9a06162e645ffcf382f966dbe79ae13aed67d82bcf3597b452343c6' 
  AND token = 'ji5d2e/X16yWwHv3zYF8FrSioyZ9WjjwMjBhcgKP3NA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}