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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc06c9897be4f1a6bf5943dd02681bf29110a014a3d6d62645a258dd0267109c' 
  AND token = '3UK5Mu5n30N6lnbB6UKDjl3X+zPr67K0XJ2SLPMN1bA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}