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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68455b50bccc8d2f01bc8d1409c9d7d4c28fe0a8a1686cc9eb31e7d024da18bf' 
  AND token = 'LiYqxCktzL7vrcyGDyUxdc8sgD0Z5gfPX8AGoVvrWWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}