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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebfb82bee9299b6981741689cdfc3251cd3510f1efaf44c4a77004591f98fdf9' 
  AND token = '2OTyZY9Ms1/OtTGDNuIGd8BN0ILYMh37Hw+SgIZ/yvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}