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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c99fe3b39acbb5aa11003e23fb2660653b05c00197cd9c509ec27e5da2d1de90' 
  AND token = 'P27Fx/ypifSfZPf9INxh91FfPu8FHzrceRr3S53Rv6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}