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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45d4f7c21800e70a05782a1dbae5de574cdf1a713e8d4296073a014a0751b0cd' 
  AND token = 'OitDrvQu13D8Azzucl5CZMa522O4SU6Rl/aywZqR9KI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}