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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c43b479a4c3262a98a818551c9a147588420724cd70b25ea6a4618f85e635aa2' 
  AND token = 'PGyiDrZNWQtLoEpCxaWITlXnNd904q/xhr4r08YAlDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}