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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34aede2c97386ecf705f17826045e905b1be0d0c84a48d11e0d38bf4ec5d0d14' 
  AND token = 'j7dSTl2hpYzjeEphPptUgRw2kf0YMeU6g9jy7FZ7/9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}